Information

» Postdoctoral Fellow, DeGrado Lab
» PhD, Massachusetts Institute of Technology, May 2007 [PhD Thesis]
» BS in Biochemistry, BS in Computer Science, University of Maryland Baltimore County, May 2002

Links

DrawCoil 1.0 - a web-based program for creating coiled-coil helical wheel diagrams
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My PhD Thesis – Computational Approaches for the Design and Prediction of Protein-Protein Interactions
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My Curriculum Vitae
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Dynamics Derivatives – a mathematical treatment of Cartesian partial derivatives of internal degrees of freedom (distance, angle, dihedral angle)

Publications

  • G. Grigoryan, A. W. Reinke, and A. E. Keating, "Design of protein-interaction specificity gives selective bZIP-binding peptides", Nature, 458, 859-864 (16 April 2009). [Abstract]

  • J. R. Apgar, S. Hahn, G. Grigoryan, and A. E. Keating, "Cluster-Expansion Models for Flexible-Backbone Protein Energetics", Journal of Computational Chemistry, 30(15), 2402 - 2413, 2009.

  • G. Grigoryan and A. E. Keating, "Structural Specificity in Coiled-coil Interactions", Current Opinion in Structural Biology, 18(4), 477 - 483, (August 2008).

  • G. Grigoryan, W. F. DeGrado, "Modest membrane hydrogen bonds deliver rich results", Nature Chemical Biology, 4, 393 - 394 (Jul 2008).

    • G. Grigoryan, A. Ochoa, A. E. Keating, "Computing van der Waals energies in the context of the rotamer approximation", Proteins: Structure, Function, and Bioinformatics, 68(4) , 863-878 (Jun 2007). [Abstract]

    G. Grigoryan, F. Zhou, S. R. Lustig, G. Ceder, D. Morgan and A. E. Keating, "Ultra-fast Evaluation of Protein Conformational Energies Directly from Sequence", PLoS Computational Biology 2(6), e63 (June 2006). [HTML] [PDF]

    F. Zhou, G. Grigoryan, S. R. Lustig, A. E. Keating, G. Ceder, and D. Morgan, "Coarse-Graining Protein Energetics in Sequence Variables", Physical Review Letters 95, 148103 (September 30, 2005). [Abstract]

    G. Grigoryan and A. E. Keating, "Structure-based prediction of bZIP partnering specificity", Journal of Molecular Biology 355, 1125-1142 (3 February, 2006). [PDF] (MIT access only) [Abstract] (free access)

  • M. H. Ali, C. M. Taylor, G. Grigoryan, K. N. Allen, B. Imperiali, and A. E. Keating, "Design of a Heterospecific, Tetrameric, 21-Residue Miniprotein with Mixed alpha/beta Structure", Structure 13(2), 225 - 234 (2005).

  • G. Grigoryan and P. Rheingans, "Point-based probabilistic surfaces to show surface uncertainty", IEEE Transactions On Visualization And Computer Graphics, 10(5): 564-573 (2004).

  • G. Grigoryan and P. Rheingans, "Probabilistic Surfaces: Point Based Primitives to Show Surface Uncertainty", Proceedings of IEEE Visualization, pages 147-153, (2002).

  • G. Grigoryan, I.T. Lima, Jr., T. Yu, V.S. Grigoryan, and C.R. Menyuk, "Using Color to Understand Light Transmission", Optics and Photonics News, 11(8), 44-50, (2000).